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ProML - the protein markup language for specification of protein sequences, structures and families

Publication Type  Journal Article
Authors  Daniel Hanisch, Ralf Zimmer, Thomas Lengauer
Year of Publication  2002
Journal  In Silico Biol
Volume  2
Number  3
Pages  313-24
Keywords  ProML
Citation Key  bioinflmu-524
Document visibility  Global publication list
Export  BibTex

Abstract

We propose a specification language ProML for protein sequences, structures, and families based on the open XML standard. The language allows for portable, system-independent, machine-parsable and human-readable representation of essential features of proteins. The language is of immediate use for several bioinformatics applications: we discuss clustering of proteins into families and the representation of the specific shared features of the respective clusters. Moreover, we use ProML for specification of data used in fold recognition bench-marks exploiting experimentally derived distance constraints.


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