@article {bioinflmu-1220, title = {{PARma: identification of microRNA target sites in AGO-PAR-CLIP data.}}, journal = {Genome biology}, volume = {14}, year = {2013}, month = {2013 Jul 29}, pages = {R79}, abstract = {PARma is a complete data analysis software for AGO-PAR-CLIP experiments to identify target sites of microRNAs as well as the microRNA binding to these sites. It integrates specific characteristics of the experiments into a generative model. The model and a novel pattern discovery tool are iteratively applied to data to estimate seed activity probabilities, cluster confidence scores and to assign the most probable microRNA. Based on differential PAR-CLIP analysis and comparison to RIP-Chip data, we show that PARma is more accurate than existing approaches. PARma is available from http://www.bio.ifi.lmu.de/PARma.}, doi = {10.1186/gb-2013-14-7-r79}, author = {Florian Erhard and Lars D{\"o}lken and Lukasz Jaskiewicz and Ralf Zimmer} }