foldChanges {StabPerf}R Documentation

Calculates fold changes.

Description

Calculates fold changes of gene expression between to sample groups.

Usage

foldChanges(data, labels, one, two, middle=mean.middle, log=TRUE)

Arguments

data a data.frame containing samples (columns) and genes (rows)
labels a factor, grouping of the samples
one the name of the first group
two the name of the second group
middle function defining a measure of central tendency, e.g. mean
log Boolean. Whether fold changes should be subjected to log2()

Details

Calculates fold changes of gene expression between to sample groups. The subsets of data are created using groupData. A middle for each row in data-groups is calculated using middle. The middle-values of two is divided by one and logged.

Value

fc list of fold changes for all spots.

See Also

groupData, pValues

Examples

data <- loadData("data/dataset.RData")
# calculate the foldChange for all spots between "normal" and "early".
fc <- foldChanges(data$x, data$y, 1, 2)

[Package StabPerf version 0.5 Index]