@article {ProSAS08,
	title = {{ProSAS: a database for analyzing alternative splicing in the context of protein structures}},
	journal = {Nucleic Acids Res.},
	volume = {36},
	year = {2008},
	month = {Jan},
	pages = {D63{\textendash}68},
	abstract = {Alternative splicing is known to be one of the major sources for
functional diversity in higher eukaryotes. Several splicing isoforms have been
characterized in the literature that play important roles in cellular processes
like apoptosis or signal transduction pathways. Splicing events can often be
detected on the mRNA level by large-scale cDNA or EST experiments and such data
is collected and annotated in several databases. Nevertheless, the effects of
splicing on the structure of a protein are largely unknown. The ProSAS (Protein
Structure and Alternative Splicing) database fills this gap and provides a
unified resource for analyzing effects of alternative splicing events in the
context of protein structures. ProSAS comprehensively annotates and models
protein structures for several Ensembl genomes as well as SwissProt entries
harbouring splicing events. Alternative isoforms annotated in Ensembl or
SwissProt can be analyzed on the protein structure and protein function level
using an intuitive user interface that provides several features and tools for a
structure-based analysis of alternative splicing events. The ProSAS database is
freely accessible at http://www.bio.ifi.lmu.de/ProSAS.},
	keywords = {prosas-08, the-prosas-database},
	doi = {10.1093/nar/gkm793},
	author = {Fabian Birzele and K{\"u}ffner, R and Meier, Franziska and Oefinger, Florian and Potthast, Christian and Ralf Zimmer}
}